When is the use of warfarin contraindicated primarily?

The use of warfarin is primarily contraindicated during pregnancy due to its potential to cross the placenta and affect fetal development. Warfarin is an anticoagulant that can lead to serious complications, such as fetal hemorrhage, teratogenic effects, and complications related to the development of fetal organs and systems. The risks associated with warfarin use during pregnancy far exceed the risks of other anticoagulants that may be used safely, making it critical for healthcare providers to avoid prescribing warfarin in this situation.

In contrast, warfarin can be resumed postpartum as it is not contraindicated after delivery, as well as before conception and during labor, depending on individual assessments and the clinical situation. Understanding these time frames helps midwives manage anticoagulant therapy effectively while minimizing risks to both the mother and developing fetus.