What clotting factors are essential for Vitamin K production?

Prepare for the New Zealand Pharmacology Exam for Midwifery Students with comprehensive flashcards and multiple-choice questions. Each question is accompanied by hints and explanations. Boost your confidence and ace your exam!

Vitamin K plays a crucial role in the synthesis of certain clotting factors within the liver, specifically factors that are necessary for proper blood coagulation. The essential clotting factors that require Vitamin K for their synthesis are factors 2 (prothrombin), 7 (proconvertin), 9 (Christmas factor), and 10 (Stuart-Prower factor).

Prothrombin, which is a key component in the clotting cascade, relies on Vitamin K for its production. Factor 7 is important for initiating the coagulation cascade upon vascular injury. Factor 9 acts as an important component within the intrinsic pathway of coagulation, while factor 10 is critical for converting prothrombin into thrombin, the enzyme that ultimately helps in the formation of fibrin clots.

The other options presented do not include the correct set of factors that are specifically synthesized with the aid of Vitamin K. Factors listed in those options either do not depend on Vitamin K or are not part of the necessary clotting cascade that relies on Vitamin K for proper clot formation.

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